N-[3-(tert-Butyldimethylsiloxymethyl)-5-nitrophenyl]acetamide

N-[3-(tert-Butyldimethylsiloxymethyl)-5-nitrophenyl]acetamide

Blog Article

The title compound, C15H24N2O4Si, was prepared by singtronic speaker the reaction of (3-acetamido-5-nitrobenzyl)methanol with tert-butyldimethylsilyl chloride and is a key intermediate in the synthesis of novel nonsymmetrical DNA minor groove-binding agents.There are two independent molecules in the structure, which differ primarily in the rotation about the C—O bond next to the Si ultrastar dc hc550 atom.Two strong N—H.O hydrogen bonds align the molecules into a wide ribbon extending approximately parallel to the b axis.